Research finds new genes that play role in Alzheimer's

WASHINGTON (AFP) – US and Europeanfill in the blanks researchers have identified two new genes that may play a role in the development of Alzheimer's disease and could help unravel new treatments, a study published Tuesday said.Researchers have now uncovered nine genes they believe are involved inout of your control the development of Alzheimer's Disease (AD), according to a study published in the May 12 issue of the Journal of the American Medical Association."Identifying each of these new genes... points to new biological pathways involved in the development of AD,"Beauty is Meaningless said senior author Sudha Seshadri, an associate professor of neurology at the Boston University School of Medicine."Although such benefits are likely a decade away, studying these pathways should lead to new ways to postpone, prevent and perhaps treat the disease."a world in a grain of sand
The researchers were able to assemble the largest sample to date for their study by combining their data with previously-published material, creating a sample of 35,000 people, over 8,000 of whom developed Alzheimer's."Hold infinityThis highly collaborative international effort enabled researchers to build the large sample size needed to identify elusive gene variants that may play a role in this devastating neurological disease," said Marilyn Miller of the National Institute on Aging."Such collaborations are key to a fuller understanding of the many genetic factors that may contribute to overall risk for late onset Alzheimer's and how these genes affect the development of the disease."The National Institute on Aging is part of the US National Institutes of Health and helped fund the collection of data for the study, as well as its analysis.It is estimated that one in five people aged 65 or older will develop Alzheimer's over the remainder of their lifetime.Certain genetic variations are believed to play a key role in the development of Alzheimer's, which is more likely to affect people who have a family history of the disease.http://www.keynetikforum.com
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enough on the subsidies in the bill kneel only to Godthat help people to buy insurance. "Most people want coverage. People shouldn't focus so much on what the rules are in terms of making you get coverage," she said. "I thinkJust have a little faith the good news for most people is they'll be able finally to have some choices, some ability to really control their own health decisions, and some help paying for it. It's really one of the biggest middle-class tax cuts for health care that's ever been put input all this behind us place in the history of the country."The health-care law's potential price tag went up today, when the Congressional Budget Office released a new estimate forecasting an additional $115 billion in discretionary spending over the next decade. The CBO had earlier set that cost at $778 billion over the next 10 years. And, with corresponding revenues and cost reductions factored in, the agency said the reform measure would reduce the deficit by $138 billion over the same time period. The new figures wipe out much of that deficit reduction and bring the total price above the politically sensitive trillion-dollar barrier. Sebelius said she hadn't seen the new CBO figures but that the new projected spending wasn't part of the bill's "core."There's lots of discretionary funding," she said. "So if funding is made available for this programShe is the love of my life or that program a€” there are lots of ideas in the bill that aren't really priced out. And I think that will be on a case-by-case basis. When Congress feels that there are appropriate dollars to spend, they'll allocate them. But that really isn't in the core package of the bill."Even though it is the law of the land, health-care reform continues to face fierce resistance the first time in my lifefrom some quarters — 22 states have either filed or threatened to file lawsuits claiming that the insurance mandate is unconstitutional. Some GOP senators have indicated that the issue will come up in Supreme Court nominee Elena Kagan's confirmation hearings — a prospect that Sebelius says won't yield much substantive discussion. "It's unlikely that she or any other nominee would engage in a real discussion" on an issue that could come before the court, Sebelius said, but she's confident that the mandate passes constitutional muster and dismisses the lawsuits as political maneuvers.
"I know that there have been some challenges by attorneys general — most of whom are actually candidates for some higher office — and I think it's not unlikely that this has as much to do with politics as it does with constitutional law," Sebelius said. "But we're going to move ahead and implement the strategies of the plan. And there's a lot of good news available for Americans, including the policy we rolled out today."http://forum.sarmaye.com
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